Stars who've battled Lyme disease: Justin Timberlake, Shania Twain, Justin Bieber, more

Justin Timberlake revealed this week he had Lyme disease, joining a growing list of celebrities who have gone public with their diagnoses.

The singer, 44, revealed he has been "battling some health issues" and was diagnosed with the bacterial-borne illness in an Instagram post on Thursday, July 31.

"If you've experienced this disease or know someone who has — then you're aware: living with this can be relentlessly debilitating, both mentally and physically," Timberlake wrote. "When I first got the diagnosis I was shocked for sure. But, at least I could understand why I would be onstage and in a massive amount of nerve pain or, just feeling crazy fatigue or sickness."

Timberlake is one of several A-listers who have shared their struggle with Lyme disease, which humans usually contract from a tick bite.

Here's a look at other stars who have been diagnosed with Lyme disease.

Justin Bieber

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Justin Bieber performs with Daniel Caesar onstage at the Coachella Stage during the 2022 Coachella Valley Music And Arts Festival on April 15, 2022, in Indio, California.

In January 2020, Justin Bieber revealed on Instagram that he was diagnosed with Lyme disease along with "a serious case of chronic mono."

"While a lot of people kept saying Justin Bieber looks like (I'm on) on meth etc. they failed to realize I've been recently diagnosed with Lyme disease," he wrote, adding, "not only that but had a serious case of chronic mono which affected my, skin, brain function, energy, and overall health."

He added: "It's been a rough couple years but getting the right treatment that will help treat this so far incurable disease and I will be back and better than ever NO CAP."

Bella, Yolanda and Anwar Hadid

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Yolanda Hadid and Bella Hadid attend God's Love We Deliver 16th Annual Golden Heart Awards at The Glasshouse on Oct. 17, 2022, in New York City.

The elder Hadid wrote about her health struggle in her 2017 memoir "Believe Me," recalling: "As difficult as these past five years have been, I am so grateful that this journey has led to me living in the light."

Bella, 28, has also been open about the toll the disease can take on the body. Alongside hospital selfies in 2023, the model wrote: "The little me that suffered would be so proud of grown me for not giving up on myself."

"Thankful to my mommy for keeping all of my medical records, sticking by me, never leaving my side, protecting, supporting, but most of all, believing me through all of this," she continued.

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Anwar Hadid attends the Elton John AIDS Foundation's 33rd Annual Academy Awards Viewing Party on March 2, 2025, in West Hollywood, California.

Anwar Hadid, younger brother to Bella, also suffers from the disease, his mother previously revealed.

At the Global Lyme Alliance inaugural gala in 2015, Yolanda spoke about the stress the illness put on the whole family.

"When my two youngest children, Bella and Anwar, were diagnosed with chronic Lyme disease in early 2012, watching my babies struggle in silence in order to support me in my journey, struck the deepest core of hopelessness inside of me," she said.

Riley Keough

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Riley Keough attends the H&M&LA Music Festival at Ace Mission Studios in Los Angeles on April 9, 2025.

The "Daisy Jones & The Six" star also shared that she was undergoing treatment at a "holistic treatment center" that "offers all kinds of things that you can't really do in America yet, like cleaning your blood."

In her family life, Keough said her health battle influenced her decision to use a surrogate for her first child, daughter Tupelo Storm Smith-Petersen.

"I think it's a very cool, selfless, and incredible act that these women do to help other people," Keough said. "I can carry children, but it felt like the best choice for what I had going on physically with the autoimmune stuff."

Ryan Sutter

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Ryan Sutter attends a WE tv event for the Marriage Boot Camp franchise at SkyBar at the Mondrian Los Angeles in West Hollywood, California, on Oct.10, 2019.

TV personality Ryan Sutter opened up about the debilitating health impacts of his Lyme disease battle during a May 2021 appearance on his wife Trista Sutter's podcast "Better Etc."

"My body would just itch for no reason, severe headaches, swollen lymph nodes, nausea, night sweats, fevers, really deep bone aches and muscle aches and joint aches, periods of extreme fatigue, almost paralyzing fatigue," said Sutter, who was frequently exposed to mold toxins in his work as a firefighter.

"The Bachelorette" alum added, "It seems like something that I will always have. It's just that now I know, and I will try to build back my immune system to fight it off."

Avril Lavigne

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Avril Lavigne

The illness, which she says she contracted from a tick, caused her extreme fatigue and joint pain, leaving the singer bedridden for months.

In an interview with USA TODAY in February 2019, she recalled a particular night during that period — lying in bed with her mom, feeling weak and convinced she was dying — that inspired her to write her song "Head Above Water."

Shania Twain

Country music icon Shania Twain contracted Lyme disease in 2003 after getting bitten by a tick while horseback riding. While she sought treatment soon after developing the illness, Twain said the disease's impact on her vocal cords went undiagnosed for years.

"There were seven years where I could not, for example, yell out for my dog. My voice would just cut out in certain places," said Twain during a 2020 appearance on "The View." "It took another several years to determine what it was. ... Nobody connected the Lyme disease to it. In the end, a neurologist finally worked out that it was the nerve to each vocal cord."

Although she had to undergo open-throat surgery to repair her vocal cords, the Grammy-winning singer reflected that the disease's toll could have been far worse.

"It was just a very unfortunate, ironic problem since I'm a singer, but I feel so grateful and so lucky that it didn't attack somewhere else because it's so debilitating," Twain added. "I have a different voice now, but I own it. I love my voice now."

Amy Schumer

Justin Bieber, Bella, Yolanda and Anwar Hadid, Riley Keough, Ryan Sutter, Avril Lavigne , Shania Twain, Amy Schumer

Amy Schumer attends the "Bunny" premiere during the 2025 Tribeca Festival at Village East Cinema in New York City on June 14, 2025.

"Anyone get LYME this summer? I got it and I'm on doxycycline," wrote Schumer in an Instagram post. "I have maybe had it for years."

Although Schumer assured her followers that she felt "good," she asked for "any advice" to "get rid of it" and treat her illness, such as, "Can you have a glass of wine or 2 on (doxycycline)?"

Contributing: Patrick Ryan, Charles Trepany and Cydney Henderson, USA TODAY