The 2025 College World Series continues on Saturday, June 21, with Coastal Carolina vs LSU in Game 1 of the CWS Finals at Charles Schwab Field Omaha in Omaha, Nebraska.

Who will win the College World Series game?

Check out some College World Series odds, College World Series picks and College World Series predictions for the game, which can be seen at 4 p.m. MST on ESPN (stream with FUBO).

Coastal Carolina advanced to the College World Series Finals with an 11-3 win over Louisville in the semifinals. LSU earned its spot with a 6-5 win over Arkansas in the semifinals.

Will Coastal Carolina or LSU win Game 1 of the 2025 College World Series championship series on June 21? CWS picks, predictions and odds weigh in on the outcome of the game.

The finals are a best-of-3 series with Game 2 scheduled for June 22 and Game 3, if necessary, on June 23.

Coastal Carolina vs LSU College World Series game odds

LSU is -166 on the moneyline, while Coastal Carolina is +130. The over/under run total is set at 8.5 runs.

LSU vs Coastal Carolina College World Series game prediction

The site warrennolan.com projects a 6-5 win for LSU over Coastal Carolina in its 2025 College World Series game result predictions.

It gives the Tigers a 54% chance to win, and it gives the Chanticleers a 46% chance to win in its projections.

College World Series game pick for Coastal Carolina vs LSU

Will LSU or Coastal Carolina win Game 1 of the College World Series Finals?

LSU is the favorite, and the higher seed (No. 6), but Coastal Carolina, the No. 13 seed, has won 26 straight games, which is truly remarkable. The Chanticleers haven't lost since April 22 and are 8-0 in the NCAA tournament.

We can't pick against a team on that kind of run.

Take Coastal Carolina to upset LSU in the first game of the 2025 College World Series championship series.

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